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Image Search Results
Journal: bioRxiv
Article Title: The interferon-ɣ inducible factor 16 (IFI16) restricts adeno-associated virus serotype 2 (AAV2) transduction in an immune-modulatory independent way
doi: 10.1101/2024.01.22.576730
Figure Lengend Snippet: KEGG pathway analysis of the cell cycle allowed the identification of differentially expressed genes in AAV2 and mock-infected cells. Upregulated genes are color coded in red, while downregulated genes are depicted in green (FC ≥ 1.5, p < 0.01, number of reads > 40). Symbol legend is shown in the KEGG pathway analysis.
Article Snippet: Heat maps of genes representing selected ontologies were constructed using
Techniques: Infection
Journal: International Journal of Molecular Sciences
Article Title: Transcriptome Analysis of Subcutaneous Adipose Tissue from Severely Obese Patients Highlights Deregulation Profiles in Coding and Non-Coding Oncogenes
doi: 10.3390/ijms22041989
Figure Lengend Snippet: Cancer and oncogene correlations in OBF vs. CTRL conditions. ( A ) Dotplot of deregulated oncogenic pathways from KEGG analysis. The y-axis represents the name of the pathway, the x-axis represents the gene ratio, dot size represents the number of different genes and the color indicates the adjusted p -value. ( B ) Relationship between DE RNAs and the possibility of a cancer diagnosis. Nodes are DE RNAs and are ranked according to fold change whereas edges indicate disease prognosis and are colored according to favorable (light blue) and unfavorable (orange) prognosis. ( C ) Pie graph displays the overall unfavorable or favorable prognosis. ( D ) Co-interaction network between lncRNAs in OBF vs. CTRL and the oncogenes highlighted after OncoScore analysis. Light blue nodes are coding genes whereas pink nodes are lncRNAs. The coding and non-coding RNAs form 4 main networks of interaction, the largest of which includes both COL4A2-AS2 and SMIM25. On the contrary, ITGB2-AS1, LINC0194 (CTEPHA1) and AL121832.2 (RPS21-AS) formed each one separate interaction network. ( E ) The GEPIA2 database displays the specific annotated expression of each lncRNA in tumoral and normal tissues.
Article Snippet: The y-axis represents the name of the pathway, the x-axis represents the gene ratio, dot size represents the number of different genes and the color indicates the adjusted p-value. (B)
Techniques: Biomarker Discovery, Expressing
Journal: International Journal of Molecular Sciences
Article Title: Transcriptome Analysis of Subcutaneous Adipose Tissue from Severely Obese Patients Highlights Deregulation Profiles in Coding and Non-Coding Oncogenes
doi: 10.3390/ijms22041989
Figure Lengend Snippet: Cancer pathways and oncogene analysis in OBT2D vs. CTRL condition. ( A ) Dotplot of deregulated oncogenic pathways from KEGG analysis. The y-axis represents the name of the pathway, the x-axis represents the gene ratio, dot size represents the number of different genes and the color indicates the adjusted p -value. ( B ) Correlation network highlights the relationship between DE RNAs and the possibility of a cancer diagnosis. Nodes are DE RNAs and are ranked according to fold change whereas edges indicate disease prognosis and are colored according to favorable (light blue) and unfavorable (orange) prognosis. ( C ) Pie graph displays the overall unfavorable or favorable prognosis. ( D ) Co-interaction network between lncRNAs on OBT2D vs. CTRL and the oncogenes highlighted after OncoScore analysis. Light blue nodes are coding genes whereas pink nodes are lncRNAs. ( D ) The GEPIA2 database displays the specific annotated expression of each lncRNA in tumoral and normal tissues.
Article Snippet: The y-axis represents the name of the pathway, the x-axis represents the gene ratio, dot size represents the number of different genes and the color indicates the adjusted p-value. (B)
Techniques: Biomarker Discovery, Expressing
Journal: International Journal of Molecular Sciences
Article Title: Transcriptome Analysis of Subcutaneous Adipose Tissue from Severely Obese Patients Highlights Deregulation Profiles in Coding and Non-Coding Oncogenes
doi: 10.3390/ijms22041989
Figure Lengend Snippet: Cancer pathways and oncogene analysis in OBT2D vs. OBF. ( A ) Dotplot of deregulated oncogenic pathways from KEGG analysis. The y-axis represents the name of the pathway, the x-axis represents the gene ratio, dot size represents the number of different genes and the color indicates the adjusted p-value. ( B ) Nodes are DE RNAs and are ranked according to fold change whereas edges indicate disease prognosis and are colored according to favorable (light blue) and unfavorable (orange) prognosis. ( C ) Pie graph displays the overall unfavorable or favorable prognosis. ( D ) Co-interaction network between lncRNAs on OBT2D vs. OBF and the oncogenes highlighted after OncoScore analysis. Four networks were built, including a total of 8 lncRNAs. ( E ) The GEPIA2 database displays the specific annotated expression of each lncRNA in tumoral and normal tissues.
Article Snippet: The y-axis represents the name of the pathway, the x-axis represents the gene ratio, dot size represents the number of different genes and the color indicates the adjusted p-value. (B)
Techniques: Expressing
Journal: International Journal of Molecular Sciences
Article Title: Transcriptome Analysis of Subcutaneous Adipose Tissue from Severely Obese Patients Highlights Deregulation Profiles in Coding and Non-Coding Oncogenes
doi: 10.3390/ijms22041989
Figure Lengend Snippet: Cancer pathways and oncogene analysis concerning gender differences. ( A ) Dotplot of deregulated oncogenic pathways from KEGG analysis. The y-axis represents the name of the pathway, the x-axis represents the gene ratio, dot size represents the number of different genes and the color indicates the adjusted p -value. ( B ) Nodes are DE RNAs and are ranked according to fold change whereas edges indicate disease prognosis and are colored according to favorable (light blue) and unfavorable (orange) prognosis. ( C ) Pie graph displays the overall unfavorable or favorable prognosis. ( D ) Co-interaction network between lncRNAs on OBT2D vs. OBF and the oncogenes highlighted after OncoScore analysis. One main network was built, including a total of 3 lncRNAs: XIST, PAX8-AS1 and JPX. ( E ) The GEPIA2 database displays the specific annotated expression of each lncRNA in tumoral and normal tissues.
Article Snippet: The y-axis represents the name of the pathway, the x-axis represents the gene ratio, dot size represents the number of different genes and the color indicates the adjusted p-value. (B)
Techniques: Expressing